描述
E.Coli Recombinant
BETAGENE Human IFN-γ



ProductCatalog No.
SpecificationShelf lifePrice

BETAGENE rhIFN-γ

GE04.1

50μg

24 months450

GE04.2

100μg600


ProductCAT. No.
VolumnShelf lifePrice

rhIFNγ

GE04.1

50μg

24 months450

GE04.2

100μg600
描述
产品描述
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Interferon-gamma (IFN-γ), also known as Type II interferon or immune interferon, is a dimerized soluble cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. It is produced primarily by CD4 and CD8 T lymphocytes as well as natural killer (NK) and natural killer T(NKT) cells. The primary role for IFN-γ is the activation of macrophages to increase phagocytosis, tumoricidal properties, and intracellular killing of pathogens. IFN-γ also increases expression of MHC antigens by macrophages and this facilitates antigen presentation to T cells. The recombinant Interferon-gamma s a 16.9 kDa protein consisting of 144 amino acid residues.
安全数据
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储存分类代码

WGK闪点(F)

13 - Non Combustible Solids

WGK 3

Not Applicable

闪点(C)

个人防护装备

Not Applicable

dust mask type N95 (US), Eyeshields, Gloves

产品信息
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  • Specs

  • Data

Appearence

Sterile Filtered White lyophilized (freeze-dried) powder.

Gene ID

15978

AA Sequence

HGTVIESLESLNNYFNSSGIDVEEKSLFLDIWRNWQKDGDMKILQSQIISFYLRLFEVLKDNQAISNNISVIESHLITTFFSNSKAKKDAFMSIAKFEVNNPQVQRQAFNELIRVVHQLLPESSLRKRKRSRC
Host E.Coli

Molecule Weight

Approximately 16.9 kDa, 144 amino acids

Biological Activity

Fully biologically active when compared to standard substance. The ED50 as measured in anti-viral assays using human HeLa cells infected with encephalomyocarditis (EMC) virus is 0.15-0.80 ng/mL, corresponding to a specific activity of 2 x 104 IU/μg.

Purity >98% by SDS-PAGE or HPLC
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, with 5% Trehalose, BSA-free.
Host Cell DNA < 0.02 ng/μg of protein
Host Cell Protein
< 0.05% when tested by ELISA
Mycoplasma Negative

Endotoxin (LAL)

< 0.01 EU/μg
Sterility Negative

Reconstitution

Before use this product, please read the direction below carefully.

1.    This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.

2.    Reconstitute in a sterile aqueous buffer to an appropriate concentration.

3.    Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stability&Storage

For long term storage, the product should be stored ≤-20°C.

Please avoid repeated freeze-thaw cycles after reconstitution.

1. At least 24 months from date of receipt, ≤-20℃ as supplied;

2. 1 month, 2 to 8 °C under sterile conditions after reconstitution;

3. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended.



Description

Interferon-gamma (IFN-γ), also known as Type II interferon or immune interferon, is a dimerized soluble cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. It is produced primarily by CD4 and CD8 T lymphocytes as well as natural killer (NK) and natural killer T(NKT) cells. The primary role for IFN-γ is the activation of macrophages to increase phagocytosis, tumoricidal properties, and intracellular killing of pathogens. IFN-γ also increases expression of MHC antigens by macrophages and this facilitates antigen presentation to T cells. The recombinant Interferon-gamma s a 16.9 kDa protein consisting of 144 amino acid residues.

Data


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