描述
E.Coli Recombinant
BETAGENE Human Interleukin-3



ProductCatalog No.
SpecificationShelf lifePrice

BETAGENE rhIL-3

GE14.1

10μg

24 months1500

GE14.2

100μg5000



ProductCAT. No.
VolumnShelf lifePrice

rhIL-3

GE14.1

10μg

24 months1500

GE14.2

100μg5000
描述
产品描述
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IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages.  The protein acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles.  Many of the IL-3 activities depend upon co-stimulation with other cytokines.  IL-3 is a species-specific, variably glycosylated cytokine.  

安全数据
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储存分类代码

WGK闪点(F)

13 - Non Combustible Solids

WGK 3

Not Applicable

闪点(C)

个人防护装备

Not Applicable

dust mask type N95 (US), Eyeshields, Gloves

  • Specs

  • DATA

Appearence

Sterile Filtered White lyophilized (freeze-dried) powder.

Gene ID

3562

AA Sequence

APMTQTTSLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF
Host E.Coli

Molecule Weight

Approximately 15kDa globular protein containing 133 amino acid residues.

Biological Activity

The ED50 as determined by a cell proliferation assay using human TF-1 cells is <0.1 ng/mL, corresponding to a specific activity of ≥ 1.0 × 107 Units/mg.
Purity >98% by SDS-PAGE or HPLC
Formulation Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, 150mM NaCl, pH7.4
Host Cell DNA< 0.02 ng/μg of protein
Host Cell Protein
< 0.05% when tested by ELISA
Mycoplasma Negative

Endotoxin (LAL)

< 0.01 EU/μg
Sterility Negative

Reconstitution

Before use this product, please read the direction below carefully.

1.    This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.

2.    Reconstitute in a sterile aqueous buffer to an appropriate concentration.

3.    Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stability&Storage

For long term storage, the product should be stored ≤-20°C.

Please avoid repeated freeze-thaw cycles after reconstitution.

1. 12 months from date of receipt, -20 to -70 °C as supplied.

2. 1 month, 2 to 8 °C under sterile conditions after reconstitution.

3. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended in our USER MANUAL



Description

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages.  The protein acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles.  Many of the IL-3 activities depend upon co-stimulation with other cytokines.  IL-3 is a species-specific, variably glycosylated cytokine.  

Data


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产品信息
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Specification Sheet
SDS
User Manual
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